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BMJ Case Rep ; 12(2)2019 Feb 21.
Artigo em Inglês | MEDLINE | ID: mdl-30796078

RESUMO

Melanocortin analogues, such as melanotan, are illegally used for artificial tanning. They have also been suggested as possible therapeutic agents in the treatment of erectile dysfunction. This case study presents a patient attending the accident and emergency department, in a tertiary urology centre, with acute priapism after abdominal subcutaneous injection of melanotan. The priapism was diagnosed as 'low-flow' and managed with cavernosal aspiration, irrigation and subsequent intracavernosal injection of phenylephrine. The patient avoided requiring surgical shunting but had not yet recovered erectile function at 4-week follow-up. Acute priapism is an unreported side effect of melanocortin analogue use and this case report presents a patient managed without surgical intervention. Future therapeutic application of these agents will need to take this potential life altering complication into consideration.


Assuntos
Melanocortinas/efeitos adversos , Pênis/efeitos dos fármacos , Peptídeos Cíclicos/efeitos adversos , Fármacos Fotossensibilizantes/efeitos adversos , Priapismo/induzido quimicamente , Recuperação de Função Fisiológica/efeitos dos fármacos , alfa-MSH/análogos & derivados , Adulto , Humanos , Masculino , Melanocortinas/farmacologia , Pênis/fisiopatologia , Peptídeos Cíclicos/farmacologia , Fármacos Fotossensibilizantes/farmacologia , Recuperação de Função Fisiológica/fisiologia , Bronzeado , Fatores de Tempo , alfa-MSH/efeitos adversos , alfa-MSH/farmacologia
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